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La Spada Laboratory
LaSpada Laboratory
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Applying the Tools of Molecular Genetics, Neuroscience, and Functional Genomics to Understand the Mechanisms of Neurodegenerative Disease
Dr. Albert La Spada  About the Lab 
Publication Spotlight 

Albert R. La Spada, MD, PhDAlbert R. La Spada, MD, PhD, is chief of the Division of Genetics in the Department of Pediatrics. An accomplished clinician and scientist, he is best known for his 1991 discovery of the first trinucleotide repeat disease mutation, setting an entirely new field of research into motion.

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UCSD-TV On Our Mind Interview 

Tracing the Molecular Roots of Neurodegenerative Diseases with Albert La Spada - On Our Mind

The LaSpada Laboratory primarily studies the molecular basis of the CAG /polyglutamine repeat diseases of which there are nine:

  • Huntington's disease
  • X-linked spinal and bulbar muscular atrophy
  • Dentatorubral-pallidoluysian atrophy
  • And six forms of spinocerebellar ataxia

Current Research